STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APW34396.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (408 aa)    
Predicted Functional Partners:
lptB
ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.981
tgt
tRNA guanosine(34) transglycosylase Tgt; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose t [...]
 
  
 0.958
APW35141.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.950
lon
Endopeptidase La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
       0.838
APW34395.1
DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family.
  
    0.744
APW33711.1
Outer membrane protein assembly factor BamA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.670
APW34399.1
Methyltransferase; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
       0.633
APW35297.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.585
APW35527.1
Alkaline protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.538
APW34400.1
Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.529
Your Current Organism:
Prevotella intermedia
NCBI taxonomy Id: 28131
Other names: ATCC 25611, Bacteroides intermedius, Bacteroides melaninogenicus subsp. intermedius, CCUG 24041, CIP 101222, CIP 103682, DSM 20706, JCM 11150, JCM 12248, NCTC 13070, P. intermedia, VPI 4197, strain Finegold B422
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