Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
APW34416.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (150 aa)    
Predicted Functional Partners:
APW34417.1
RNA polymerase Rpb6; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
 
     0.871
bamD
Outer membrane protein assembly factor BamD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.799
APW34415.1
Cell division protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.633
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
       0.605
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
  
     0.588
APW34414.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.524
rnpA
Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
  
     0.479
APW34406.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.475
APW35051.1
RNA pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.465
APW33628.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.428
Your Current Organism:
Prevotella intermedia
NCBI taxonomy Id: 28131
Other names: ATCC 25611, Bacteroides intermedius, Bacteroides melaninogenicus subsp. intermedius, CCUG 24041, CIP 101222, CIP 103682, DSM 20706, JCM 11150, JCM 12248, NCTC 13070, P. intermedia, VPI 4197, strain Finegold B422
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