| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APW33614.1 | APW34474.1 | BWX40_01400 | BWX40_06280 | TonB-dependent receptor; Derived by automated computational analysis using gene prediction method: Protein Homology. | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.415 |
| APW34474.1 | APW33614.1 | BWX40_06280 | BWX40_01400 | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | TonB-dependent receptor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.415 |
| APW34474.1 | APW34968.1 | BWX40_06280 | BWX40_09120 | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.520 |
| APW34474.1 | APW35166.1 | BWX40_06280 | BWX40_09570 | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Mobilization protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.442 |
| APW34474.1 | APW35603.1 | BWX40_06280 | BWX40_12170 | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Mobilization protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.442 |
| APW34474.1 | FolC | BWX40_06280 | BWX40_06285 | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. | 0.530 |
| APW34474.1 | dnaJ | BWX40_06280 | BWX40_06290 | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.490 |
| APW34474.1 | grpE | BWX40_06280 | BWX40_06295 | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.424 |
| APW34968.1 | APW34474.1 | BWX40_09120 | BWX40_06280 | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.520 |
| APW35166.1 | APW34474.1 | BWX40_09570 | BWX40_06280 | Mobilization protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.442 |
| APW35603.1 | APW34474.1 | BWX40_12170 | BWX40_06280 | Mobilization protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.442 |
| FolC | APW34474.1 | BWX40_06285 | BWX40_06280 | Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.530 |
| FolC | dnaJ | BWX40_06285 | BWX40_06290 | Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.829 |
| FolC | grpE | BWX40_06285 | BWX40_06295 | Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. | Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.688 |
| dnaJ | APW34474.1 | BWX40_06290 | BWX40_06280 | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.490 |
| dnaJ | FolC | BWX40_06290 | BWX40_06285 | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. | 0.829 |
| dnaJ | grpE | BWX40_06290 | BWX40_06295 | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.983 |
| grpE | APW34474.1 | BWX40_06295 | BWX40_06280 | Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.424 |
| grpE | FolC | BWX40_06295 | BWX40_06285 | Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. | 0.688 |
| grpE | dnaJ | BWX40_06295 | BWX40_06290 | Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.983 |