STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
APW34576.1Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (656 aa)    
Predicted Functional Partners:
APW34575.1
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.870
APW34577.1
AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.718
APW34410.1
Glycosyl transferase family 2; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.664
APW33766.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.574
APW34691.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
   0.546
gcvT
Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine.
   
  0.523
dpp7
Peptidase S10; Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.
  
     0.516
APW34574.1
Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.506
ThyA_2
Thymidylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.500
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
     
  0.500
Your Current Organism:
Prevotella intermedia
NCBI taxonomy Id: 28131
Other names: ATCC 25611, Bacteroides intermedius, Bacteroides melaninogenicus subsp. intermedius, CCUG 24041, CIP 101222, CIP 103682, DSM 20706, JCM 11150, JCM 12248, NCTC 13070, P. intermedia, VPI 4197, strain Finegold B422
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