Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
APW34718.1Alpha-2-macroglobulin; Derived by automated computational analysis using gene prediction method: Protein Homology. (1879 aa)    
Predicted Functional Partners:
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
       0.820
APW35477.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.578
APW33559.1
N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.458
APW34340.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.431
APW35131.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.428
APW34755.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.422
APW33726.1
AP endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.409
RnhA
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase H family.
  
     0.405
Your Current Organism:
Prevotella intermedia
NCBI taxonomy Id: 28131
Other names: ATCC 25611, Bacteroides intermedius, Bacteroides melaninogenicus subsp. intermedius, CCUG 24041, CIP 101222, CIP 103682, DSM 20706, JCM 11150, JCM 12248, NCTC 13070, P. intermedia, VPI 4197, strain Finegold B422
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