Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BWX40_07905Hypothetical protein; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (837 aa)    
Predicted Functional Partners:
APW35297.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.768
APW33419.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.709
BWX40_10310
Lipoprotein signal peptidase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.697
APW33551.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.683
APW34325.1
Hemin receptor; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.666
APW35553.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.663
MtnN
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
       0.657
LuxS
S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
       0.641
APW35442.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.634
bamD
Outer membrane protein assembly factor BamD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.628
Your Current Organism:
Prevotella intermedia
NCBI taxonomy Id: 28131
Other names: ATCC 25611, Bacteroides intermedius, Bacteroides melaninogenicus subsp. intermedius, CCUG 24041, CIP 101222, CIP 103682, DSM 20706, JCM 11150, JCM 12248, NCTC 13070, P. intermedia, VPI 4197, strain Finegold B422
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