Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
APW34804.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)    
Predicted Functional Partners:
APW34805.1
Helix-turn-helix transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.643
thiC
Phosphomethylpyrimidine synthase ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
  
 0.614
thiE
Thiamine phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.553
APW35317.1
NADH-quinone oxidoreductase subunit C; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.542
ThiD
Bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.510
APW35057.1
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.510
APW35169.1
SNF2/RAD54 family helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.503
APW34803.1
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.495
APW33647.1
Thiamine phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.484
APW34518.1
Thiamine phosphate pyrophosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.484
Your Current Organism:
Prevotella intermedia
NCBI taxonomy Id: 28131
Other names: ATCC 25611, Bacteroides intermedius, Bacteroides melaninogenicus subsp. intermedius, CCUG 24041, CIP 101222, CIP 103682, DSM 20706, JCM 11150, JCM 12248, NCTC 13070, P. intermedia, VPI 4197, strain Finegold B422
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