STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APW34959.1DNA topoisomerase II; Derived by automated computational analysis using gene prediction method: Protein Homology. (122 aa)    
Predicted Functional Partners:
APW35567.1
Rubrerythrin; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.902
APW35372.1
Ferritin; Iron-storage protein.
  
  
 0.658
APW33828.1
FprA family A-type flavoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.565
APW35191.1
Rubredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.552
APW34961.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.547
APW34960.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.545
APW34962.1
RNA polymerase subunit sigma-70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily.
       0.545
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
   
  
 0.518
APW33632.1
Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.506
APW33788.1
Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.506
Your Current Organism:
Prevotella intermedia
NCBI taxonomy Id: 28131
Other names: ATCC 25611, Bacteroides intermedius, Bacteroides melaninogenicus subsp. intermedius, CCUG 24041, CIP 101222, CIP 103682, DSM 20706, JCM 11150, JCM 12248, NCTC 13070, P. intermedia, VPI 4197, strain Finegold B422
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