Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
APW35150.1LacI family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)    
Predicted Functional Partners:
APW35002.1
MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.784
APW35004.1
RagB/SusD family nutrient uptake outer membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.782
APW35003.1
SusC/RagA family TonB-linked outer membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.749
APW34974.1
Alpha-amylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 13 family.
 
  
 0.662
APW35006.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.583
APW35363.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.540
APW34682.1
Aldose epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.498
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
    
   0.448
ribBA
Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
   0.448
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 
 0.432
Your Current Organism:
Prevotella intermedia
NCBI taxonomy Id: 28131
Other names: ATCC 25611, Bacteroides intermedius, Bacteroides melaninogenicus subsp. intermedius, CCUG 24041, CIP 101222, CIP 103682, DSM 20706, JCM 11150, JCM 12248, NCTC 13070, P. intermedia, VPI 4197, strain Finegold B422
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