Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PepD_1Aminoacyl-histidine dipeptidase; Catalyzes the hydrolysis of Xaa-His dipeptides; Derived by automated computational analysis using gene prediction method: Protein Homology. (483 aa)    
Predicted Functional Partners:
PepD_2
Aminoacyl-histidine dipeptidase; Catalyzes the hydrolysis of Xaa-His dipeptides; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.913
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
 
 0.835
APW33837.1
Cystathionine beta-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.802
APW35332.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.663
APW35333.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.610
APW35331.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.435
APW34112.1
Nif3-like dinuclear metal center hexameric protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.426
Your Current Organism:
Prevotella intermedia
NCBI taxonomy Id: 28131
Other names: ATCC 25611, Bacteroides intermedius, Bacteroides melaninogenicus subsp. intermedius, CCUG 24041, CIP 101222, CIP 103682, DSM 20706, JCM 11150, JCM 12248, NCTC 13070, P. intermedia, VPI 4197, strain Finegold B422
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