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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
QueA_1S-adenosylmethionine tRNA ribosyltransferase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (424 aa)    
Predicted Functional Partners:
tgt
tRNA guanosine(34) transglycosylase Tgt; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose t [...]
 
 0.963
APW35401.1
Phosphatase PAP2 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.803
batB
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.775
batC
Aerotolerance regulator BatC; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.775
APW35299.1
tRNA epoxyqueuosine(34) reductase QueG; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.747
batD
Aerotolerance regulator BatD; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.711
batA
VWA domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.685
APW35396.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.658
APW35395.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.651
APW35394.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.607
Your Current Organism:
Prevotella intermedia
NCBI taxonomy Id: 28131
Other names: ATCC 25611, Bacteroides intermedius, Bacteroides melaninogenicus subsp. intermedius, CCUG 24041, CIP 101222, CIP 103682, DSM 20706, JCM 11150, JCM 12248, NCTC 13070, P. intermedia, VPI 4197, strain Finegold B422
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