Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
APW35440.1Hemolysin; Derived by automated computational analysis using gene prediction method: Protein Homology. (419 aa)    
Predicted Functional Partners:
APW35441.1
LPS export ABC transporter periplasmic protein LptC; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.825
APW35442.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.783
APW35439.1
Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.637
APW35443.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.623
APW35444.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.526
secA
Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.
  
  
 0.417
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
     
 0.406
Your Current Organism:
Prevotella intermedia
NCBI taxonomy Id: 28131
Other names: ATCC 25611, Bacteroides intermedius, Bacteroides melaninogenicus subsp. intermedius, CCUG 24041, CIP 101222, CIP 103682, DSM 20706, JCM 11150, JCM 12248, NCTC 13070, P. intermedia, VPI 4197, strain Finegold B422
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