Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
APW35654.1Cell filamentation protein Fic; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)    
Predicted Functional Partners:
BWX40_12065
Hypothetical protein; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.775
APW34739.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.565
HsdM
Type I restriction-modification system subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.522
APW35586.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.504
APW35587.1
Restriction endonuclease subunit R; Subunit R is required for both nuclease and ATPase activities, but not for modification.
       0.492
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.423
APW35588.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.421
APW33781.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.410
Alr
Bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase/alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
     
 0.405
nnrD
Bifunctional ADP-dependent (S)-NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-spec [...]
     
 0.404
Your Current Organism:
Prevotella intermedia
NCBI taxonomy Id: 28131
Other names: ATCC 25611, Bacteroides intermedius, Bacteroides melaninogenicus subsp. intermedius, CCUG 24041, CIP 101222, CIP 103682, DSM 20706, JCM 11150, JCM 12248, NCTC 13070, P. intermedia, VPI 4197, strain Finegold B422
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