STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
actPCation acetate symporter; Member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (561 aa)    
Predicted Functional Partners:
KXB29453.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.982
KXB29921.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.918
KXB30068.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.906
KXB32725.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.703
KXB32724.1
Nucleotidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.678
KXB32723.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.467
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.462
KXB30033.1
acetoacetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.462
prpE
propionate--CoA ligase; Catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.462
KXB29634.1
Dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.437
Your Current Organism:
Dechloromonas denitrificans
NCBI taxonomy Id: 281362
Other names: ATCC BAA-841, D. denitrificans, DSM 15892, Dechloromonas denitrificans Horn et al. 2005, strain ED1
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