node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKE93710.1 | AKE94855.1 | CSK29544_00747 | CSK29544_01897 | Hypothetical protein. | anti-RNA polymerase sigma factor SigE; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic protea [...] | 0.639 |
AKE93710.1 | AKE95189.1 | CSK29544_00747 | CSK29544_02232 | Hypothetical protein. | Hypothetical protein. | 0.651 |
AKE93710.1 | AKE96552.1 | CSK29544_00747 | CSK29544_03605 | Hypothetical protein. | Hypothetical protein. | 0.625 |
AKE93710.1 | AKE96892.1 | CSK29544_00747 | CSK29544_03947 | Hypothetical protein. | LexA regulated protein. | 0.642 |
AKE93710.1 | fabR | CSK29544_00747 | CSK29544_00754 | Hypothetical protein. | Transcriptional regulator; Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer. | 0.607 |
AKE93710.1 | hdfR | CSK29544_00747 | CSK29544_00748 | Hypothetical protein. | Hypothetical protein; Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon. | 0.617 |
AKE93710.1 | lptC | CSK29544_00747 | CSK29544_00568 | Hypothetical protein. | Lipopolysaccharide export system protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.760 |
AKE93710.1 | metJ | CSK29544_00747 | CSK29544_00772 | Hypothetical protein. | Transcriptional repressor; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.692 |
AKE93710.1 | rraB | CSK29544_00747 | CSK29544_00401 | Hypothetical protein. | Ribonuclease E inhibitor; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.672 |
AKE93710.1 | yihI | CSK29544_00747 | CSK29544_00971 | Hypothetical protein. | GTPase activator; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. | 0.685 |
AKE94855.1 | AKE93710.1 | CSK29544_01897 | CSK29544_00747 | anti-RNA polymerase sigma factor SigE; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic protea [...] | Hypothetical protein. | 0.639 |
AKE94855.1 | AKE95189.1 | CSK29544_01897 | CSK29544_02232 | anti-RNA polymerase sigma factor SigE; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic protea [...] | Hypothetical protein. | 0.666 |
AKE94855.1 | AKE96552.1 | CSK29544_01897 | CSK29544_03605 | anti-RNA polymerase sigma factor SigE; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic protea [...] | Hypothetical protein. | 0.715 |
AKE94855.1 | fabR | CSK29544_01897 | CSK29544_00754 | anti-RNA polymerase sigma factor SigE; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic protea [...] | Transcriptional regulator; Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer. | 0.405 |
AKE94855.1 | lptC | CSK29544_01897 | CSK29544_00568 | anti-RNA polymerase sigma factor SigE; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic protea [...] | Lipopolysaccharide export system protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.763 |
AKE94855.1 | metJ | CSK29544_01897 | CSK29544_00772 | anti-RNA polymerase sigma factor SigE; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic protea [...] | Transcriptional repressor; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.477 |
AKE94855.1 | rraB | CSK29544_01897 | CSK29544_00401 | anti-RNA polymerase sigma factor SigE; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic protea [...] | Ribonuclease E inhibitor; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.677 |
AKE94855.1 | yihI | CSK29544_01897 | CSK29544_00971 | anti-RNA polymerase sigma factor SigE; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic protea [...] | GTPase activator; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. | 0.650 |
AKE95189.1 | AKE93710.1 | CSK29544_02232 | CSK29544_00747 | Hypothetical protein. | Hypothetical protein. | 0.651 |
AKE95189.1 | AKE94855.1 | CSK29544_02232 | CSK29544_01897 | Hypothetical protein. | anti-RNA polymerase sigma factor SigE; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic protea [...] | 0.666 |