STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKE93892.1Transcriptional regulator; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. (241 aa)    
Predicted Functional Partners:
pstB
Phosphate ABC transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
  
 0.992
AKE93894.1
Phosphate transporter permease subunit PtsA.
  
 0.991
AKE93895.1
Phosphate transporter permease subunit PstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
  
 0.907
AKE93896.1
Phosphate ABC transporter substrate-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.
 
  
 0.810
AKE97120.1
Phosphate regulon sensor protein PhoR.
 
   
 0.673
AKE93041.1
YaeQ protein.
   
    0.643
phoB
Transcriptional regulator PhoB.
  
 0.589
AKE93891.1
Endo-1,4-beta-xylanase A precursor.
     
 0.567
AKE93535.1
RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.553
parC
DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule (By similarity). Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
   
  
 0.546
Your Current Organism:
Cronobacter sakazakii
NCBI taxonomy Id: 28141
Other names: ATCC 29544, C. sakazakii, CCUG 14558, CDC 4562-70 (78-067947), CIP 103183, Cronobacter sakazakii subsp. sakazakii, DSM 4485, Enterobacter sakazakii, LMG 5740, LMG:5740, NBRC 102416, NCTC 11467, yellow -pigmented Enterobacter cloacae
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