Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gmmGDP-mannose mannosyl hydrolase; Hydrolyzes GDP-mannose; Belongs to the Nudix hydrolase family. (159 aa)    
Predicted Functional Partners:
fcl
GDP-L-fucose synthetase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
  
 0.997
gmd
GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
 
  
 0.996
AKE95444.1
Glycosyl transferase WcaI.
 
  
 0.996
wcaC
Colanic acid biosynthesis glycosyltransferase WcaC.
 
  
 0.934
AKE95440.1
Colanic acid biosynthesis acetyltransferase WcaF.
 
  
 0.901
AKE95439.1
Glycosyl transferase WcaE.
 
  
 0.874
AKE95447.1
UDP-glucose lipid carrier transferase.
 
  
 0.835
manC
Mannose-1-phosphate guanyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
  
 0.834
AKE95446.1
Phosphomannomutase.
     
 0.712
wcaA
Colanic acid biosynthesis glycosyltransferase WcaA.
 
    0.706
Your Current Organism:
Cronobacter sakazakii
NCBI taxonomy Id: 28141
Other names: ATCC 29544, C. sakazakii, CCUG 14558, CDC 4562-70 (78-067947), CIP 103183, Cronobacter sakazakii subsp. sakazakii, DSM 4485, Enterobacter sakazakii, LMG 5740, LMG:5740, NBRC 102416, NCTC 11467, yellow -pigmented Enterobacter cloacae
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.