STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKE96312.1Hydrogenase nickel incorporation protein HypB. (290 aa)    
Predicted Functional Partners:
AKE96313.1
Hydrogenase assembly chaperone HypC/HupF.
  
 0.997
hypA
Putative hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.993
AKE96314.1
Hydrogenase isoenzymes formation protein HypD; Belongs to the HypD family.
 
  
 0.988
AKE96306.1
Formate hydrogenlyase subunit V.
 
 
 
 0.973
AKE96315.1
Hydrogenase expression/formation protein HypE.
 
  
 0.970
AKE96296.1
Carbamoyltransferase; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
   
 0.859
AKE94236.1
Peptidyl-prolyl cis-trans isomerase.
    
 
 0.707
AKE96316.1
Formate hydrogenlyase transcriptional activator.
     
 0.596
AKE93208.1
Peptidyl-prolyl cis-trans isomerase.
    
 
 0.589
AKE96310.1
Formate hydrogenlyase regulatory protein HycA.
  
    0.523
Your Current Organism:
Cronobacter sakazakii
NCBI taxonomy Id: 28141
Other names: ATCC 29544, C. sakazakii, CCUG 14558, CDC 4562-70 (78-067947), CIP 103183, Cronobacter sakazakii subsp. sakazakii, DSM 4485, Enterobacter sakazakii, LMG 5740, LMG:5740, NBRC 102416, NCTC 11467, yellow -pigmented Enterobacter cloacae
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