node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKE94404.1 | AKE96846.1 | CSK29544_01443 | CSK29544_03901 | Mechanosensitive ion channel protein. | Cell envelope integrity inner membrane protein TolA. | 0.599 |
AKE94404.1 | AKE97083.1 | CSK29544_01443 | CSK29544_04142 | Mechanosensitive ion channel protein. | Hypothetical protein. | 0.578 |
AKE94404.1 | lptC | CSK29544_01443 | CSK29544_00568 | Mechanosensitive ion channel protein. | Lipopolysaccharide export system protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.445 |
AKE94855.1 | AKE96846.1 | CSK29544_01897 | CSK29544_03901 | anti-RNA polymerase sigma factor SigE; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic protea [...] | Cell envelope integrity inner membrane protein TolA. | 0.614 |
AKE94855.1 | AKE97083.1 | CSK29544_01897 | CSK29544_04142 | anti-RNA polymerase sigma factor SigE; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic protea [...] | Hypothetical protein. | 0.740 |
AKE94855.1 | lapA | CSK29544_01897 | CSK29544_02876 | anti-RNA polymerase sigma factor SigE; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic protea [...] | Putative inner membrane protein YciS; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | 0.766 |
AKE94855.1 | lptC | CSK29544_01897 | CSK29544_00568 | anti-RNA polymerase sigma factor SigE; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic protea [...] | Lipopolysaccharide export system protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.763 |
AKE96846.1 | AKE94404.1 | CSK29544_03901 | CSK29544_01443 | Cell envelope integrity inner membrane protein TolA. | Mechanosensitive ion channel protein. | 0.599 |
AKE96846.1 | AKE94855.1 | CSK29544_03901 | CSK29544_01897 | Cell envelope integrity inner membrane protein TolA. | anti-RNA polymerase sigma factor SigE; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic protea [...] | 0.614 |
AKE96846.1 | AKE96849.1 | CSK29544_03901 | CSK29544_03904 | Cell envelope integrity inner membrane protein TolA. | acyl-CoA thioester hydrolase YbgC. | 0.701 |
AKE96846.1 | AKE97083.1 | CSK29544_03901 | CSK29544_04142 | Cell envelope integrity inner membrane protein TolA. | Hypothetical protein. | 0.610 |
AKE96846.1 | cpoB | CSK29544_03901 | CSK29544_03898 | Cell envelope integrity inner membrane protein TolA. | Tol-pal system protein YbgF; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. | 0.718 |
AKE96846.1 | lapA | CSK29544_03901 | CSK29544_02876 | Cell envelope integrity inner membrane protein TolA. | Putative inner membrane protein YciS; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | 0.608 |
AKE96846.1 | lptC | CSK29544_03901 | CSK29544_00568 | Cell envelope integrity inner membrane protein TolA. | Lipopolysaccharide export system protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.731 |
AKE96846.1 | tolB | CSK29544_03901 | CSK29544_03900 | Cell envelope integrity inner membrane protein TolA. | Translocation protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane. | 0.858 |
AKE96846.1 | tolQ | CSK29544_03901 | CSK29544_03903 | Cell envelope integrity inner membrane protein TolA. | Colicin uptake protein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. | 0.761 |
AKE96846.1 | tolR | CSK29544_03901 | CSK29544_03902 | Cell envelope integrity inner membrane protein TolA. | Colicin uptake protein TolR; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. | 0.973 |
AKE96849.1 | AKE96846.1 | CSK29544_03904 | CSK29544_03901 | acyl-CoA thioester hydrolase YbgC. | Cell envelope integrity inner membrane protein TolA. | 0.701 |
AKE96849.1 | cpoB | CSK29544_03904 | CSK29544_03898 | acyl-CoA thioester hydrolase YbgC. | Tol-pal system protein YbgF; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. | 0.554 |
AKE96849.1 | tolB | CSK29544_03904 | CSK29544_03900 | acyl-CoA thioester hydrolase YbgC. | Translocation protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane. | 0.605 |