STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hyfGNickel-dependent hydrogenase family protein; [C] COG3261 Ni,Fe-hydrogenase III large subunit. (594 aa)    
Predicted Functional Partners:
hyfB
NADH-Ubiquinone/plastoquinone (complex I), various chains family protein; [CP] COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit.
 
 
 0.999
hyfC
NADH dehydrogenase family protein; [C] COG0650 Formate hydrogenlyase subunit 4.
 
 
 0.999
hyfF
NADH-Ubiquinone/plastoquinone (complex I), various chains family protein; [CP] COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit.
 
 
 0.999
hyfH
4Fe-4S dicluster domain protein; [C] COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I).
 
 
 0.999
hyfI
NADH ubiquinone oxidoreductase, 20 Kd subunit; [C] COG3260 Ni,Fe-hydrogenase III small subunit.
 
 0.999
hyfE
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L family protein; [C] COG4237 Hydrogenase 4 membrane component (E).
 
  
 0.996
fdhF_2
Fdh-alpha: formate dehydrogenase, alpha subunit; [C] COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 
 0.992
hyfD
NADH-Ubiquinone/plastoquinone (complex I), various chains family protein; [CP] COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit.
 
 
 0.990
CH54_2070
Fdh-alpha: formate dehydrogenase, alpha subunit; [C] COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing.
 
 
 0.989
hyfA
4Fe-4S dicluster domain protein; [C] COG1142 Fe-S-cluster-containing hydrogenase components 2.
 
 
 0.988
Your Current Organism:
Yersinia kristensenii
NCBI taxonomy Id: 28152
Other names: ATCC 33638, CCUG 11294, CCUG 8241, CIP 80.30, DSM 18543, JCM 7576, NCTC 11471, Y. kristensenii, strain 105
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.