STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
trg_3Conserved hypothetical protein; [NT] COG0840 Methyl-accepting chemotaxis protein. (552 aa)    
Predicted Functional Partners:
cheW
cheW-like domain protein; [NT] COG0835 Chemotaxis signal transduction protein.
 
 0.995
cheA
Signal transducing histidine kinase, homodimeric domain protein; [NT] COG0643 Chemotaxis protein histidine kinase and related kinases.
 
 0.995
cheV
Response regulator; [NT] COG0835 Chemotaxis signal transduction protein.
 
 0.993
cheR
Methyltransferase domain protein; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
 
 0.986
cheB
cheB methylesterase family protein; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.985
cheY
Response regulator; [T] COG0784 FOG: CheY-like receiver.
  
  0.956
CH54_585
GGDEF: diguanylate cyclase domain protein; [T] COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.
 
 
 0.724
adrA_2
GGDEF: diguanylate cyclase domain protein; [T] COG2202 FOG: PAS/PAC domain.
 
 
 0.658
CH54_46
Bacterial extracellular solute-binding s, 3 family protein; [ET] COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.
  
 
 0.617
gmr_1
GGDEF: diguanylate cyclase domain protein; [T] COG2202 FOG: PAS/PAC domain.
  
 
 0.566
Your Current Organism:
Yersinia kristensenii
NCBI taxonomy Id: 28152
Other names: ATCC 33638, CCUG 11294, CCUG 8241, CIP 80.30, DSM 18543, JCM 7576, NCTC 11471, Y. kristensenii, strain 105
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