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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
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mdeAOAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase family protein; [E] COG2873 O-acetylhomoserine sulfhydrylase. (425 aa)    
Predicted Functional Partners:
metA
Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.
 
 
 0.970
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.965
uptG
CBS domain protein; [E] COG0031 Cysteine synthase.
 
 
 0.954
metC
cysta_beta_ly_B: cystathionine beta-lyase; [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.
 
 
0.943
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.938
metB
O_succ_thio_ly: O-succinylhomoserine (thiol)-lyase; [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.
 
 
0.936
malY
C_S_lyase_PatB: C-S lyase family protein; [E] COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities.
   
 0.933
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
   
 
 0.927
thrA
Asp_kinase: aspartate kinase domain protein; [E] COG0460 Homoserine dehydrogenase; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.918
metL
Asp_kinase: aspartate kinase domain protein; [E] COG0527 Aspartokinases; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.918
Your Current Organism:
Yersinia kristensenii
NCBI taxonomy Id: 28152
Other names: ATCC 33638, CCUG 11294, CCUG 8241, CIP 80.30, DSM 18543, JCM 7576, NCTC 11471, Y. kristensenii, strain 105
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