STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CH54_1456Alpha-2-macroglobulin family protein; Protects the bacterial cell from host peptidases. (1678 aa)    
Predicted Functional Partners:
pbpC
PBP_1c: penicillin-binding protein 1C; [M] COG4953 Membrane carboxypeptidase/penicillin-binding protein PbpC.
 
   
 0.936
nrdR
Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
    
   0.570
CH54_397
Hypothetical protein.
 
  
 0.546
CH54_3825
[N] COG5492 Bacterial surface proteins containing Ig-like domains.
  
     0.538
creD
[V] COG4452 Inner membrane protein involved in colicin E2 resistance.
  
     0.482
CH54_837
Acyltransferase family protein; [I] COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase.
   
    0.449
CH54_349
Zinc carboxypeptidase family protein; [E] COG2866 Predicted carboxypeptidase.
    
 0.440
CH54_1454
beta/Gamma crystallin family protein.
 
     0.432
sfiA
Cell division inhibitor SulA family protein; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
  
     0.408
Your Current Organism:
Yersinia kristensenii
NCBI taxonomy Id: 28152
Other names: ATCC 33638, CCUG 11294, CCUG 8241, CIP 80.30, DSM 18543, JCM 7576, NCTC 11471, Y. kristensenii, strain 105
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.