| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CH54_2806 | igaA | CH54_2806 | CH54_2314 | Conserved hypothetical protein; [S] COG3776 Predicted membrane protein. | Intracellular growth attenuator IgaA family protein. | 0.711 |
| CH54_2806 | pagP | CH54_2806 | CH54_151 | Conserved hypothetical protein; [S] COG3776 Predicted membrane protein. | Antimicrobial peptide resistance and lipid A acylation PagP family protein; Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors. | 0.650 |
| CH54_2806 | yhjW | CH54_2806 | CH54_2427 | Conserved hypothetical protein; [S] COG3776 Predicted membrane protein. | Conserved hypothetical protein; [R] COG2194 Predicted membrane-associated, metal-dependent hydrolase. | 0.438 |
| CH54_851 | arnT | CH54_851 | CH54_268 | [O] COG3555 Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases. | Dolichyl-phosphate-mannose-mannosyltransferase family protein; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family. | 0.918 |
| CH54_851 | eptA | CH54_851 | CH54_309 | [O] COG3555 Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases. | Conserved hypothetical protein; [R] COG2194 Predicted membrane-associated, metal-dependent hydrolase. | 0.918 |
| CH54_851 | msbB | CH54_851 | CH54_615 | [O] COG3555 Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases. | Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A. | 0.914 |
| CH54_851 | pagP | CH54_851 | CH54_151 | [O] COG3555 Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases. | Antimicrobial peptide resistance and lipid A acylation PagP family protein; Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors. | 0.919 |
| CH54_851 | yhjW | CH54_851 | CH54_2427 | [O] COG3555 Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases. | Conserved hypothetical protein; [R] COG2194 Predicted membrane-associated, metal-dependent hydrolase. | 0.901 |
| arnT | CH54_851 | CH54_268 | CH54_851 | Dolichyl-phosphate-mannose-mannosyltransferase family protein; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family. | [O] COG3555 Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases. | 0.918 |
| arnT | eptA | CH54_268 | CH54_309 | Dolichyl-phosphate-mannose-mannosyltransferase family protein; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family. | Conserved hypothetical protein; [R] COG2194 Predicted membrane-associated, metal-dependent hydrolase. | 0.950 |
| arnT | lpxK | CH54_268 | CH54_4100 | Dolichyl-phosphate-mannose-mannosyltransferase family protein; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.919 |
| arnT | msbB | CH54_268 | CH54_615 | Dolichyl-phosphate-mannose-mannosyltransferase family protein; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family. | Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A. | 0.921 |
| arnT | pagP | CH54_268 | CH54_151 | Dolichyl-phosphate-mannose-mannosyltransferase family protein; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family. | Antimicrobial peptide resistance and lipid A acylation PagP family protein; Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors. | 0.955 |
| arnT | waaA | CH54_268 | CH54_2651 | Dolichyl-phosphate-mannose-mannosyltransferase family protein; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family. | Glycosyl transferases group 1 family protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.923 |
| arnT | yhjW | CH54_268 | CH54_2427 | Dolichyl-phosphate-mannose-mannosyltransferase family protein; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family. | Conserved hypothetical protein; [R] COG2194 Predicted membrane-associated, metal-dependent hydrolase. | 0.925 |
| cmr | pagP | CH54_2451 | CH54_151 | Sugar (and other) transporter family protein; [GEPR] COG0477 Permeases of the major facilitator superfamily. | Antimicrobial peptide resistance and lipid A acylation PagP family protein; Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors. | 0.601 |
| eptA | CH54_851 | CH54_309 | CH54_851 | Conserved hypothetical protein; [R] COG2194 Predicted membrane-associated, metal-dependent hydrolase. | [O] COG3555 Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases. | 0.918 |
| eptA | arnT | CH54_309 | CH54_268 | Conserved hypothetical protein; [R] COG2194 Predicted membrane-associated, metal-dependent hydrolase. | Dolichyl-phosphate-mannose-mannosyltransferase family protein; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family. | 0.950 |
| eptA | msbB | CH54_309 | CH54_615 | Conserved hypothetical protein; [R] COG2194 Predicted membrane-associated, metal-dependent hydrolase. | Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A. | 0.913 |
| eptA | pagP | CH54_309 | CH54_151 | Conserved hypothetical protein; [R] COG2194 Predicted membrane-associated, metal-dependent hydrolase. | Antimicrobial peptide resistance and lipid A acylation PagP family protein; Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors. | 0.931 |