STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ureDureD urease accessory family protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. (327 aa)    
Predicted Functional Partners:
ureF
ureF family protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.998
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
 
 0.993
ureB
Urease_beta: urease, beta subunit; [E] COG0832 Urea amidohydrolase (urease) beta subunit; Belongs to the urease beta subunit family.
 
 
 0.984
ureA
Urease_gam: urease, gamma subunit; [E] COG0831 Urea amidohydrolase (urease) gamma subunit; Belongs to the urease gamma subunit family.
 
 
 0.980
ureE
Hypothetical protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
  
 0.967
ureC
Urease_alph: urease, alpha subunit; [E] COG0804 Urea amidohydrolase (urease) alpha subunit.
 
  
 0.940
yut
Urea_trans_yut: urea transporter; [E] COG4413 Urea transporter.
 
   
 0.928
hypB
hypB: hydrogenase accessory protein HypB; [OK] COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase.
  
 
 0.886
hoxN
Nico: transition metal uptake transporter, Ni2+-Co2+ transporter family protein; [P] COG3376 High-affinity nickel permease; Belongs to the NiCoT transporter (TC 2.A.52) family.
     
 0.622
CH54_1643
Periplasmic binding domain protein; [E] COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.
 
   
 0.452
Your Current Organism:
Yersinia kristensenii
NCBI taxonomy Id: 28152
Other names: ATCC 33638, CCUG 11294, CCUG 8241, CIP 80.30, DSM 18543, JCM 7576, NCTC 11471, Y. kristensenii, strain 105
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