STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sdaASda_mono: L-serine ammonia-lyase; [E] COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (454 aa)    
Predicted Functional Partners:
glyA
Beta-eliminating lyase family protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.955
cysE
cysE: serine O-acetyltransferase; [E] COG1045 Serine acetyltransferase.
     
 0.914
tdcB
Pyridoxal-phosphate dependent enzyme family protein; [E] COG1171 Threonine dehydratase.
  
 
 0.913
ilvA
ilvA_2Cterm: threonine ammonia-lyase, biosynthetic; [E] COG1171 Threonine dehydratase.
  
 
 0.913
uptG
CBS domain protein; [E] COG0031 Cysteine synthase.
  
 
 0.908
serB
serB: phosphoserine phosphatase SerB; [E] COG0560 Phosphoserine phosphatase.
   
 
 0.907
sdaB
Sda_mono: L-serine ammonia-lyase; [E] COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
 
 
0.903
pssA
Phospholipase D family protein; [I] COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes.
     
  0.900
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
  0.900
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
   
 
  0.900
Your Current Organism:
Yersinia kristensenii
NCBI taxonomy Id: 28152
Other names: ATCC 33638, CCUG 11294, CCUG 8241, CIP 80.30, DSM 18543, JCM 7576, NCTC 11471, Y. kristensenii, strain 105
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