STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
macB_2ABC transporter family protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family. (658 aa)    
Predicted Functional Partners:
macB_6
ABC transporter family protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
0.999
CH54_1034
Putative membrane protein.
  
 
 0.995
CH54_1664
RND_mfp: efflux transporter, RND family, MFP subunit; [M] COG0845 Membrane-fusion protein.
 
 
 0.994
cusC
outer_NodT: efflux transporter, outer membrane factor (OMF) lipo, NodT family protein; [MU] COG1538 Outer membrane protein.
 
 
 0.978
macA_4
RND_mfp: efflux transporter, RND family, MFP subunit; [M] COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.976
acrA
RND_mfp: efflux transporter, RND family, MFP subunit; [M] COG0845 Membrane-fusion protein.
 
 
 0.922
lolE_2
ftsX-like permease family protein; [V] COG0577 ABC-type antimicrobial peptide transport system, permease component.
 
 
 0.906
cusB
RND_mfp: efflux transporter, RND family, MFP subunit; [M] COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 
 0.904
CH54_1035
RND_mfp: efflux transporter, RND family, MFP subunit; [M] COG0845 Membrane-fusion protein.
  
 
 0.902
mdtE
RND_mfp: efflux transporter, RND family, MFP subunit; [M] COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 
 0.902
Your Current Organism:
Yersinia kristensenii
NCBI taxonomy Id: 28152
Other names: ATCC 33638, CCUG 11294, CCUG 8241, CIP 80.30, DSM 18543, JCM 7576, NCTC 11471, Y. kristensenii, strain 105
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.