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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CH54_1925N-6 DNA Methylase family protein; [V] COG0286 Type I restriction-modification system methyltransferase subunit. (787 aa)    
Predicted Functional Partners:
CH54_1924
Hypothetical protein.
 
 
 0.998
CH54_1921
Hypothetical protein; Type I restriction enzyme R N terminus family protein; [V] COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases.
 
 
 0.994
CH54_1522
Type III restriction enzyme, res subunit.
  
 
 0.915
CH54_1525
AAA domain protein; [L] COG3593 Predicted ATP-dependent endonuclease of the OLD family.
  
  
 0.658
CH54_2090
AAA domain protein; [L] COG3593 Predicted ATP-dependent endonuclease of the OLD family.
  
  
 0.658
CH54_4066
AAA domain protein; [L] COG3593 Predicted ATP-dependent endonuclease of the OLD family.
  
  
 0.658
CH54_757
Conserved hypothetical protein; [K] COG0640 Predicted transcriptional regulators.
  
    0.629
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
 
 0.614
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.473
kdsD
kpsF: sugar isomerase, KpsF/GutQ family protein; [M] COG0794 Predicted sugar phosphate isomerase involved in capsule formation.
   
 
 0.470
Your Current Organism:
Yersinia kristensenii
NCBI taxonomy Id: 28152
Other names: ATCC 33638, CCUG 11294, CCUG 8241, CIP 80.30, DSM 18543, JCM 7576, NCTC 11471, Y. kristensenii, strain 105
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