STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kduDkduD: 2-deoxy-D-gluconate 3-dehydrogenase; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (253 aa)    
Predicted Functional Partners:
CH54_233
kduI/IolB family protein; [G] COG3717 5-keto 4-deoxyuronate isomerase.
 
 
 0.991
uxaA_2
Hypothetical protein; D-galactarate dehydratase / Altronate hydrolase, C terminus family protein; [G] COG2721 Altronate dehydratase.
  
  
 0.948
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
 
 
 0.938
kdgK
pfkB carbohydrate kinase family protein; [G] COG0524 Sugar kinases, ribokinase family.
  
 0.899
nuoD
NADH dehydrogenase (quinone), D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.
   
 
 0.892
gnd
6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
  
 0.817
rpe
Rpe: ribulose-phosphate 3-epimerase; [G] COG0036 Pentose-5-phosphate-3-epimerase.
     
 0.803
rpiA
Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
     
 0.803
CH54_234
Cupin domain protein; [S] COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain.
 
   
 0.767
pfkB
pfkB: 1-phosphofructokinase; [G] COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family.
   
    0.632
Your Current Organism:
Yersinia kristensenii
NCBI taxonomy Id: 28152
Other names: ATCC 33638, CCUG 11294, CCUG 8241, CIP 80.30, DSM 18543, JCM 7576, NCTC 11471, Y. kristensenii, strain 105
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.