STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cvaA_2hlyD secretion family protein; [M] COG0845 Membrane-fusion protein. (425 aa)    
Predicted Functional Partners:
apxIB_3
ABC transporter family protein; [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain.
 
   0.971
hlyB
ABC transporter family protein; [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain.
 
   0.865
macB_2
ABC transporter family protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
  
 
 0.749
macB_6
ABC transporter family protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.749
tolC
type_I_sec_TolC: type I secretion outer membrane, TolC family protein; [MU] COG1538 Outer membrane protein.
 
 
 0.693
apxIB_2
type_I_sec_HlyB: type I secretion system ATPase family protein; [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain.
 
   0.606
apxIB_1
type_I_sec_HlyB: type I secretion system ATPase family protein; [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain.
 
   0.603
lagD
ABC transporter family protein; [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain.
 
   0.598
CH54_3972
type_I_sec_LssB: type I secretion system ATPase family protein; [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain.
 
   0.585
CH54_3971
type_I_sec_TolC: type I secretion outer membrane, TolC family protein; [MU] COG1538 Outer membrane protein.
  
 
 0.578
Your Current Organism:
Yersinia kristensenii
NCBI taxonomy Id: 28152
Other names: ATCC 33638, CCUG 11294, CCUG 8241, CIP 80.30, DSM 18543, JCM 7576, NCTC 11471, Y. kristensenii, strain 105
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