| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| acs | aidB | CH54_2204 | CH54_2029 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Hypothetical protein; acyl-CoA dehydrogenase, C-terminal domain protein; [I] COG1960 Acyl-CoA dehydrogenases. | 0.556 |
| acs | echA8 | CH54_2204 | CH54_2587 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | enoyl-CoA hydratase/isomerase family protein; [I] COG1024 Enoyl-CoA hydratase/carnithine racemase. | 0.602 |
| acs | fadA | CH54_2204 | CH54_2851 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | acetyl-CoA C-acyltransferase FadA; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. | 0.939 |
| acs | fadB | CH54_2204 | CH54_2852 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.984 |
| acs | fadE | CH54_2204 | CH54_3579 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Hypothetical protein; acyl-CoA dehydrogenase, C-terminal domain protein; [I] COG1960 Acyl-CoA dehydrogenases. | 0.596 |
| acs | fadI | CH54_2204 | CH54_3858 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | acetyl-CoA C-acyltransferase FadI; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. | 0.979 |
| acs | fadJ | CH54_2204 | CH54_3859 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Fatty oxidation complex, alpha subunit FadJ; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.980 |
| acs | gltA | CH54_2204 | CH54_1152 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | cit_synth_I: citrate (Si)-synthase; [C] COG0372 Citrate synthase; Belongs to the citrate synthase family. | 0.990 |
| acs | mmsA | CH54_2204 | CH54_2370 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | MMSDH: methylmalonate-semialdehyde dehydrogenase; [C] COG1012 NAD-dependent aldehyde dehydrogenases. | 0.955 |
| acs | pta | CH54_2204 | CH54_3913 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.945 |
| aidB | acs | CH54_2029 | CH54_2204 | Hypothetical protein; acyl-CoA dehydrogenase, C-terminal domain protein; [I] COG1960 Acyl-CoA dehydrogenases. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.556 |
| aidB | echA8 | CH54_2029 | CH54_2587 | Hypothetical protein; acyl-CoA dehydrogenase, C-terminal domain protein; [I] COG1960 Acyl-CoA dehydrogenases. | enoyl-CoA hydratase/isomerase family protein; [I] COG1024 Enoyl-CoA hydratase/carnithine racemase. | 0.883 |
| aidB | fadA | CH54_2029 | CH54_2851 | Hypothetical protein; acyl-CoA dehydrogenase, C-terminal domain protein; [I] COG1960 Acyl-CoA dehydrogenases. | acetyl-CoA C-acyltransferase FadA; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. | 0.893 |
| aidB | fadB | CH54_2029 | CH54_2852 | Hypothetical protein; acyl-CoA dehydrogenase, C-terminal domain protein; [I] COG1960 Acyl-CoA dehydrogenases. | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.975 |
| aidB | fadI | CH54_2029 | CH54_3858 | Hypothetical protein; acyl-CoA dehydrogenase, C-terminal domain protein; [I] COG1960 Acyl-CoA dehydrogenases. | acetyl-CoA C-acyltransferase FadI; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. | 0.906 |
| aidB | fadJ | CH54_2029 | CH54_3859 | Hypothetical protein; acyl-CoA dehydrogenase, C-terminal domain protein; [I] COG1960 Acyl-CoA dehydrogenases. | Fatty oxidation complex, alpha subunit FadJ; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.978 |
| echA8 | acs | CH54_2587 | CH54_2204 | enoyl-CoA hydratase/isomerase family protein; [I] COG1024 Enoyl-CoA hydratase/carnithine racemase. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.602 |
| echA8 | aidB | CH54_2587 | CH54_2029 | enoyl-CoA hydratase/isomerase family protein; [I] COG1024 Enoyl-CoA hydratase/carnithine racemase. | Hypothetical protein; acyl-CoA dehydrogenase, C-terminal domain protein; [I] COG1960 Acyl-CoA dehydrogenases. | 0.883 |
| echA8 | fadA | CH54_2587 | CH54_2851 | enoyl-CoA hydratase/isomerase family protein; [I] COG1024 Enoyl-CoA hydratase/carnithine racemase. | acetyl-CoA C-acyltransferase FadA; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. | 0.972 |
| echA8 | fadB | CH54_2587 | CH54_2852 | enoyl-CoA hydratase/isomerase family protein; [I] COG1024 Enoyl-CoA hydratase/carnithine racemase. | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.513 |