Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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allS_4Bacterial regulatory helix-turn-helix, lysR family protein; [K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (308 aa)    
Predicted Functional Partners:
ydhC
efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily protein; [GEPR] COG0477 Permeases of the major facilitator superfamily.
 
     0.690
CH54_329
Bacterial regulatory helix-turn-helix, lysR family protein; [K] COG0583 Transcriptional regulator.
  
     0.497
lysR
Bacterial regulatory helix-turn-helix, lysR family protein; [K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.422
gltR
Bacterial regulatory helix-turn-helix, lysR family protein; [K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.420
dmlR_10
Bacterial regulatory helix-turn-helix, lysR family protein; [K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.411
gltB
Glutamine amidotransferases class-II family protein; [E] COG0070 Glutamate synthase domain 3.
     
 0.408
dmlR_2
Bacterial regulatory helix-turn-helix, lysR family protein; [K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.405
nhaR
Bacterial regulatory helix-turn-helix, lysR family protein; [K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.404
nsrR
Rrf2_super: Rrf2 family protein; [K] COG1959 Predicted transcriptional regulator.
  
     0.402
Your Current Organism:
Yersinia kristensenii
NCBI taxonomy Id: 28152
Other names: ATCC 33638, CCUG 11294, CCUG 8241, CIP 80.30, DSM 18543, JCM 7576, NCTC 11471, Y. kristensenii, strain 105
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