CH54_3112 protein (Yersinia kristensenii) - STRING interaction network

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Score

CH54_3112

CYTH domain protein; [S] COG3025 Uncharacterized conserved protein. (454 aa)

Predicted Functional Partners:

glnE

0.732

yihI

0.657

yfbV

0.643

ccmI

0.548

CH54_3111

0.499

pspB

0.499

sixA

0.497

rfaE1

0.459

syd

0.435

CH54_3365

0.434

Your Current Organism:

Yersinia kristensenii

NCBI taxonomy Id: 28152
Other names: ATCC 33638, CCUG 11294, CCUG 8241, CIP 80.30, DSM 18543, JCM 7576, NCTC 11471, Y. kristensenii, strain 105

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CH54_3111	CH54_3112	CH54_3111	CH54_3112	[T] COG3103 SH3 domain protein.	CYTH domain protein; [S] COG3025 Uncharacterized conserved protein.	0.499
CH54_3111	glnE	CH54_3111	CH54_3113	[T] COG3103 SH3 domain protein.	Glutamate-ammonia ligase adenylyltransferase family protein; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds th [...]	0.531
CH54_3112	CH54_3111	CH54_3112	CH54_3111	CYTH domain protein; [S] COG3025 Uncharacterized conserved protein.	[T] COG3103 SH3 domain protein.	0.499
CH54_3112	CH54_3365	CH54_3112	CH54_3365	CYTH domain protein; [S] COG3025 Uncharacterized conserved protein.	Hypothetical protein.	0.434
CH54_3112	ccmI	CH54_3112	CH54_3854	CYTH domain protein; [S] COG3025 Uncharacterized conserved protein.	cytochro_ccmI: cytochrome c-type biogenesis protein CcmI; [O] COG4235 Cytochrome c biogenesis factor.	0.548
CH54_3112	glnE	CH54_3112	CH54_3113	CYTH domain protein; [S] COG3025 Uncharacterized conserved protein.	Glutamate-ammonia ligase adenylyltransferase family protein; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds th [...]	0.732
CH54_3112	pspB	CH54_3112	CH54_340	CYTH domain protein; [S] COG3025 Uncharacterized conserved protein.	phageshock_pspB: phage shock protein B.	0.499
CH54_3112	rfaE1	CH54_3112	CH54_3114	CYTH domain protein; [S] COG3025 Uncharacterized conserved protein.	Bifunctional protein RfaE, domain I; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.	0.459
CH54_3112	sixA	CH54_3112	CH54_3860	CYTH domain protein; [S] COG3025 Uncharacterized conserved protein.	sixA: phosphohistidine phosphatase SixA; [T] COG2062 Phosphohistidine phosphatase SixA.	0.497
CH54_3112	syd	CH54_3112	CH54_3512	CYTH domain protein; [S] COG3025 Uncharacterized conserved protein.	Syd family protein; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family.	0.435
CH54_3112	yfbV	CH54_3112	CH54_3915	CYTH domain protein; [S] COG3025 Uncharacterized conserved protein.	Conserved hypothetical protein; [S] COG3092 Uncharacterized protein conserved in bacteria.	0.643
CH54_3112	yihI	CH54_3112	CH54_2562	CYTH domain protein; [S] COG3025 Uncharacterized conserved protein.	Der GTPase activator family protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.	0.657
CH54_3365	CH54_3112	CH54_3365	CH54_3112	Hypothetical protein.	CYTH domain protein; [S] COG3025 Uncharacterized conserved protein.	0.434
CH54_3365	yfbV	CH54_3365	CH54_3915	Hypothetical protein.	Conserved hypothetical protein; [S] COG3092 Uncharacterized protein conserved in bacteria.	0.602
CH54_3365	yihI	CH54_3365	CH54_2562	Hypothetical protein.	Der GTPase activator family protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.	0.546
ccmI	CH54_3112	CH54_3854	CH54_3112	cytochro_ccmI: cytochrome c-type biogenesis protein CcmI; [O] COG4235 Cytochrome c biogenesis factor.	CYTH domain protein; [S] COG3025 Uncharacterized conserved protein.	0.548
ccmI	yihI	CH54_3854	CH54_2562	cytochro_ccmI: cytochrome c-type biogenesis protein CcmI; [O] COG4235 Cytochrome c biogenesis factor.	Der GTPase activator family protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.	0.459
glnE	CH54_3111	CH54_3113	CH54_3111	Glutamate-ammonia ligase adenylyltransferase family protein; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds th [...]	[T] COG3103 SH3 domain protein.	0.531
glnE	CH54_3112	CH54_3113	CH54_3112	Glutamate-ammonia ligase adenylyltransferase family protein; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds th [...]	CYTH domain protein; [S] COG3025 Uncharacterized conserved protein.	0.732
glnE	rfaE1	CH54_3113	CH54_3114	Glutamate-ammonia ligase adenylyltransferase family protein; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds th [...]	Bifunctional protein RfaE, domain I; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.	0.491