STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dmlR_10Bacterial regulatory helix-turn-helix, lysR family protein; [K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (307 aa)    
Predicted Functional Partners:
parE
DNA topoisomerase IV, B subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
       0.709
CH54_916
Bacterial regulatory helix-turn-helix, lysR family protein; [K] COG0583 Transcriptional regulator.
  
     0.530
gltC_1
Bacterial regulatory helix-turn-helix, lysR family protein; Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.
  
     0.527
cpdA
Calcineurin-like phosphoesterase family protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
  
    0.458
CH54_3125
Conserved hypothetical protein; [R] COG3150 Predicted esterase.
       0.456
cbl
Bacterial regulatory helix-turn-helix, lysR family protein; [K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.443
allS_4
Bacterial regulatory helix-turn-helix, lysR family protein; [K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.411
oxyR_2
Bacterial regulatory helix-turn-helix, lysR family protein; [K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.405
Your Current Organism:
Yersinia kristensenii
NCBI taxonomy Id: 28152
Other names: ATCC 33638, CCUG 11294, CCUG 8241, CIP 80.30, DSM 18543, JCM 7576, NCTC 11471, Y. kristensenii, strain 105
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