STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hybC_1Nickel-dependent hydrogenase family protein; [C] COG0374 Ni,Fe-hydrogenase I large subunit. (564 aa)    
Predicted Functional Partners:
hyb0
hydA: hydrogenase family protein; [C] COG1740 Ni,Fe-hydrogenase I small subunit.
 
 0.999
hypA-2
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.986
hybD
hupD: hydrogenase expression/formation protein; [C] COG0680 Ni,Fe-hydrogenase maturation factor.
 
 
 0.981
hybB
Putative membrane protein; [C] COG5557 Polysulphide reductase.
 
  
 0.980
hybE
hydrog_HybE: [NiFe] hydrogenase assembly chaperone, HybE family domain protein.
 
  
 0.979
hypD
hypD: hydrogenase expression/formation protein HypD; [O] COG0409 Hydrogenase maturation factor; Belongs to the HypD family.
 
 
 0.966
hybA
4Fe-4S dicluster domain protein; [C] COG0437 Fe-S-cluster-containing hydrogenase components 1.
 
  
 0.965
hypC-2
hypC_hupF: hydrogenase assembly chaperone HypC/HupF; [O] COG0298 Hydrogenase maturation factor.
 
 
 0.949
hypB
hypB: hydrogenase accessory protein HypB; [OK] COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase.
 
   
 0.947
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.927
Your Current Organism:
Yersinia kristensenii
NCBI taxonomy Id: 28152
Other names: ATCC 33638, CCUG 11294, CCUG 8241, CIP 80.30, DSM 18543, JCM 7576, NCTC 11471, Y. kristensenii, strain 105
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