node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
dam | dam-2 | CH54_2303 | CH54_2629 | Dam: DNA adenine methylase family protein; [L] COG0338 Site-specific DNA methylase. | Dam: DNA adenine methylase family protein; [L] COG0338 Site-specific DNA methylase. | 0.907 |
dam | metJ | CH54_2303 | CH54_2691 | Dam: DNA adenine methylase family protein; [L] COG0338 Site-specific DNA methylase. | Met Apo-repressor, MetJ family protein; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.575 |
dam | mutH | CH54_2303 | CH54_3483 | Dam: DNA adenine methylase family protein; [L] COG0338 Site-specific DNA methylase. | DNA mismatch repair endonuclease MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family. | 0.763 |
dam | proQ | CH54_2303 | CH54_216 | Dam: DNA adenine methylase family protein; [L] COG0338 Site-specific DNA methylase. | proQ/FINO family protein; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family. | 0.478 |
dam | rraB | CH54_2303 | CH54_1935 | Dam: DNA adenine methylase family protein; [L] COG0338 Site-specific DNA methylase. | Regulator of ribonuclease activity B family protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.452 |
dam | seqA | CH54_2303 | CH54_1172 | Dam: DNA adenine methylase family protein; [L] COG0338 Site-specific DNA methylase. | seqA family protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.415 |
dam-2 | dam | CH54_2629 | CH54_2303 | Dam: DNA adenine methylase family protein; [L] COG0338 Site-specific DNA methylase. | Dam: DNA adenine methylase family protein; [L] COG0338 Site-specific DNA methylase. | 0.907 |
dam-2 | metJ | CH54_2629 | CH54_2691 | Dam: DNA adenine methylase family protein; [L] COG0338 Site-specific DNA methylase. | Met Apo-repressor, MetJ family protein; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.412 |
dam-2 | mutH | CH54_2629 | CH54_3483 | Dam: DNA adenine methylase family protein; [L] COG0338 Site-specific DNA methylase. | DNA mismatch repair endonuclease MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family. | 0.729 |
fadR | metJ | CH54_590 | CH54_2691 | Fatty acid metabolism transcriptional regulator FadR; Multifunctional regulator of fatty acid metabolism. | Met Apo-repressor, MetJ family protein; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.691 |
fadR | mutH | CH54_590 | CH54_3483 | Fatty acid metabolism transcriptional regulator FadR; Multifunctional regulator of fatty acid metabolism. | DNA mismatch repair endonuclease MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family. | 0.696 |
fadR | proQ | CH54_590 | CH54_216 | Fatty acid metabolism transcriptional regulator FadR; Multifunctional regulator of fatty acid metabolism. | proQ/FINO family protein; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family. | 0.734 |
fadR | rraB | CH54_590 | CH54_1935 | Fatty acid metabolism transcriptional regulator FadR; Multifunctional regulator of fatty acid metabolism. | Regulator of ribonuclease activity B family protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.709 |
fadR | seqA | CH54_590 | CH54_1172 | Fatty acid metabolism transcriptional regulator FadR; Multifunctional regulator of fatty acid metabolism. | seqA family protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.758 |
fadR | yfbV | CH54_590 | CH54_3915 | Fatty acid metabolism transcriptional regulator FadR; Multifunctional regulator of fatty acid metabolism. | Conserved hypothetical protein; [S] COG3092 Uncharacterized protein conserved in bacteria. | 0.691 |
fadR | yihI | CH54_590 | CH54_2562 | Fatty acid metabolism transcriptional regulator FadR; Multifunctional regulator of fatty acid metabolism. | Der GTPase activator family protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. | 0.608 |
metJ | dam | CH54_2691 | CH54_2303 | Met Apo-repressor, MetJ family protein; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | Dam: DNA adenine methylase family protein; [L] COG0338 Site-specific DNA methylase. | 0.575 |
metJ | dam-2 | CH54_2691 | CH54_2629 | Met Apo-repressor, MetJ family protein; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | Dam: DNA adenine methylase family protein; [L] COG0338 Site-specific DNA methylase. | 0.412 |
metJ | fadR | CH54_2691 | CH54_590 | Met Apo-repressor, MetJ family protein; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | Fatty acid metabolism transcriptional regulator FadR; Multifunctional regulator of fatty acid metabolism. | 0.691 |
metJ | mutH | CH54_2691 | CH54_3483 | Met Apo-repressor, MetJ family protein; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | DNA mismatch repair endonuclease MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family. | 0.729 |