STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fpr_1PTS_HPr_: phosphocarrier, HPr family protein; [G] COG4668 Mannitol/fructose-specific phosphotransferase system, IIA domain. (378 aa)    
Predicted Functional Partners:
ptsP
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 0.999
fruA
FRU: PTS system, Fru family, IIB component domain protein; [G] COG1299 Phosphotransferase system, fructose-specific IIC component.
 
 
 0.999
pfkB
pfkB: 1-phosphofructokinase; [G] COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family.
 
  
 0.994
mtlA
mtlA: PTS system, mannitol-specific IIC component family protein; [G] COG2213 Phosphotransferase system, mannitol-specific IIBC component.
 
 
0.986
ptsP-2
PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase; [T] COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family.
 
 
 
 0.976
dhaM
Dha_pts: dihydroxyacetone kinase, phosphotransfer subunit; [S] COG3412 Uncharacterized protein conserved in bacteria; Belongs to the PEP-utilizing enzyme family.
 
0.967
hpr
PTS_HPr_: phosphocarrier, HPr family protein; [G] COG1925 Phosphotransferase system, HPr-related proteins.
 
 
0.946
mtlD2
Mannitol dehydrogenase Rossmann domain protein; [G] COG0246 Mannitol-1-phosphate/altronate dehydrogenases.
  
 0.923
manX
Pts-sorbose: PTS system, mannose/fructose/sorbose, IIB component family protein; [G] COG3444 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB.
   
 
 0.898
nagE
PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component; [G] COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.
 
 
 0.863
Your Current Organism:
Yersinia kristensenii
NCBI taxonomy Id: 28152
Other names: ATCC 33638, CCUG 11294, CCUG 8241, CIP 80.30, DSM 18543, JCM 7576, NCTC 11471, Y. kristensenii, strain 105
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