| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CH54_3363 | CH54_4067 | CH54_3363 | CH54_4067 | Conserved hypothetical protein; [S] COG3171 Uncharacterized protein conserved in bacteria. | Conserved hypothetical protein; [S] COG2990 Uncharacterized protein conserved in bacteria. | 0.410 |
| CH54_3363 | yejM | CH54_3363 | CH54_3988 | Conserved hypothetical protein; [S] COG3171 Uncharacterized protein conserved in bacteria. | Type I phosphodiesterase / nucleotide pyrophosphatase family protein; [R] COG3083 Predicted hydrolase of alkaline phosphatase superfamily. | 0.491 |
| CH54_4067 | CH54_3363 | CH54_4067 | CH54_3363 | Conserved hypothetical protein; [S] COG2990 Uncharacterized protein conserved in bacteria. | Conserved hypothetical protein; [S] COG3171 Uncharacterized protein conserved in bacteria. | 0.410 |
| CH54_4067 | ampE | CH54_4067 | CH54_1759 | Conserved hypothetical protein; [S] COG2990 Uncharacterized protein conserved in bacteria. | [V] COG3725 Membrane protein required for beta-lactamase induction. | 0.473 |
| CH54_4067 | appA_1 | CH54_4067 | CH54_831 | Conserved hypothetical protein; [S] COG2990 Uncharacterized protein conserved in bacteria. | Histidine phosphatase super family protein. | 0.490 |
| CH54_4067 | macA_4 | CH54_4067 | CH54_4068 | Conserved hypothetical protein; [S] COG2990 Uncharacterized protein conserved in bacteria. | RND_mfp: efflux transporter, RND family, MFP subunit; [M] COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.501 |
| CH54_4067 | macB_6 | CH54_4067 | CH54_4069 | Conserved hypothetical protein; [S] COG2990 Uncharacterized protein conserved in bacteria. | ABC transporter family protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.563 |
| CH54_4067 | tsgA | CH54_4067 | CH54_2293 | Conserved hypothetical protein; [S] COG2990 Uncharacterized protein conserved in bacteria. | [GEPR] COG0477 Permeases of the major facilitator superfamily. | 0.472 |
| CH54_4067 | yeeA | CH54_4067 | CH54_969 | Conserved hypothetical protein; [S] COG2990 Uncharacterized protein conserved in bacteria. | Fusaric acid resistance family protein; [S] COG1289 Predicted membrane protein. | 0.684 |
| CH54_4067 | yejM | CH54_4067 | CH54_3988 | Conserved hypothetical protein; [S] COG2990 Uncharacterized protein conserved in bacteria. | Type I phosphodiesterase / nucleotide pyrophosphatase family protein; [R] COG3083 Predicted hydrolase of alkaline phosphatase superfamily. | 0.510 |
| ampE | CH54_4067 | CH54_1759 | CH54_4067 | [V] COG3725 Membrane protein required for beta-lactamase induction. | Conserved hypothetical protein; [S] COG2990 Uncharacterized protein conserved in bacteria. | 0.473 |
| ampE | tsgA | CH54_1759 | CH54_2293 | [V] COG3725 Membrane protein required for beta-lactamase induction. | [GEPR] COG0477 Permeases of the major facilitator superfamily. | 0.726 |
| ampE | yeeA | CH54_1759 | CH54_969 | [V] COG3725 Membrane protein required for beta-lactamase induction. | Fusaric acid resistance family protein; [S] COG1289 Predicted membrane protein. | 0.725 |
| appA_1 | CH54_4067 | CH54_831 | CH54_4067 | Histidine phosphatase super family protein. | Conserved hypothetical protein; [S] COG2990 Uncharacterized protein conserved in bacteria. | 0.490 |
| appA_1 | tsgA | CH54_831 | CH54_2293 | Histidine phosphatase super family protein. | [GEPR] COG0477 Permeases of the major facilitator superfamily. | 0.537 |
| macA_4 | CH54_4067 | CH54_4068 | CH54_4067 | RND_mfp: efflux transporter, RND family, MFP subunit; [M] COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Conserved hypothetical protein; [S] COG2990 Uncharacterized protein conserved in bacteria. | 0.501 |
| macA_4 | macB_6 | CH54_4068 | CH54_4069 | RND_mfp: efflux transporter, RND family, MFP subunit; [M] COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | ABC transporter family protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.995 |
| macB_6 | CH54_4067 | CH54_4069 | CH54_4067 | ABC transporter family protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Conserved hypothetical protein; [S] COG2990 Uncharacterized protein conserved in bacteria. | 0.563 |
| macB_6 | macA_4 | CH54_4069 | CH54_4068 | ABC transporter family protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | RND_mfp: efflux transporter, RND family, MFP subunit; [M] COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.995 |
| tsgA | CH54_4067 | CH54_2293 | CH54_4067 | [GEPR] COG0477 Permeases of the major facilitator superfamily. | Conserved hypothetical protein; [S] COG2990 Uncharacterized protein conserved in bacteria. | 0.472 |