STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
manAmanA: mannose-6-phosphate isomerase, class I; [G] COG1482 Phosphomannose isomerase; Belongs to the mannose-6-phosphate isomerase type 1 family. (391 aa)    
Predicted Functional Partners:
manX
Pts-sorbose: PTS system, mannose/fructose/sorbose, IIB component family protein; [G] COG3444 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB.
    
 0.944
pgi
Phosphoglucose isomerase family protein; [G] COG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.942
nagB
Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
     
 0.926
glmS
Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
     
 0.919
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.919
mak
Glucokinase family protein; [KG] COG1940 Transcriptional regulator/sugar kinase.
  
 
 0.915
mtlD2
Mannitol dehydrogenase Rossmann domain protein; [G] COG0246 Mannitol-1-phosphate/altronate dehydrogenases.
     
 0.914
manZ_2
EIID-AGA: PTS system, mannose/fructose/sorbose, IID component family protein; [G] COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID.
    
  0.910
manY_2
EII-Sor: PTS system, mannose/fructose/sorbose, IIC component family protein; [G] COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC.
    
  0.910
fbp
Fructose-1-6-bisphosphatase family protein; [G] COG0158 Fructose-1,6-bisphosphatase; Belongs to the FBPase class 1 family.
     
 0.909
Your Current Organism:
Yersinia kristensenii
NCBI taxonomy Id: 28152
Other names: ATCC 33638, CCUG 11294, CCUG 8241, CIP 80.30, DSM 18543, JCM 7576, NCTC 11471, Y. kristensenii, strain 105
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.