Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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addAden_deam: adenosine deaminase; [F] COG1816 Adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. (332 aa)    
Predicted Functional Partners:
xapA
XAPA: xanthosine phosphorylase; [F] COG0005 Purine nucleoside phosphorylase.
  
 
 0.937
deoD
deoD: purine nucleoside phosphorylase; [F] COG0813 Purine-nucleoside phosphorylase.
    
 0.931
gsk
pfkB carbohydrate kinase family protein; [G] COG0524 Sugar kinases, ribokinase family.
  
 
 0.930
ushA
Hypothetical protein; 5'-nucleotidase, C-terminal domain protein; [F] COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family.
 
  
 0.921
surE
5'/3'-nucleotidase SurE; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.
     
 0.909
ppnP
Hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
     
 0.909
yfkN
Hypothetical protein; 5'-nucleotidase, C-terminal domain protein; [F] COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family.
    
 0.907
cpdB
cycNucDiestase: 2',3'-cyclic-nucleotide 2'-phosphodiesterase; [F] COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family.
    
 0.907
nagD
HAD-SF-IA-v1: HAD hydrolase, IA, variant 1 family protein; [G] COG0647 Predicted sugar phosphatases of the HAD superfamily.
     
 0.904
yfiH_2
Multi-copper polyphenol oxidoreductase laccase family protein; [S] COG1496 Uncharacterized conserved protein; Belongs to the multicopper oxidase YfiH/RL5 family.
    
  0.900
Your Current Organism:
Yersinia kristensenii
NCBI taxonomy Id: 28152
Other names: ATCC 33638, CCUG 11294, CCUG 8241, CIP 80.30, DSM 18543, JCM 7576, NCTC 11471, Y. kristensenii, strain 105
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