STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
apxIB_2type_I_sec_HlyB: type I secretion system ATPase family protein; [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain. (708 aa)    
Predicted Functional Partners:
hlyD_1
type_I_hlyD: type I secretion membrane fusion, HlyD family protein; [M] COG0845 Membrane-fusion protein.
 
 0.976
apxIB_1
type_I_sec_HlyB: type I secretion system ATPase family protein; [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain.
 
    
0.799
CH54_89
hlyD secretion family protein; [M] COG0845 Membrane-fusion protein.
 
   0.789
prsE
type_I_hlyD: type I secretion membrane fusion, HlyD family protein; [M] COG0845 Membrane-fusion protein.
 
 0.726
hlyD_2
type_I_hlyD: type I secretion membrane fusion, HlyD family protein; [M] COG0845 Membrane-fusion protein.
 
 0.713
CH54_1170
Hemolysin-type calcium-binding repeat family protein; [Q] COG2931 RTX toxins and related Ca2+-binding proteins.
 
  
 0.689
viuB_2
[P] COG2375 Siderophore-interacting protein.
   
   0.668
cvaA_2
hlyD secretion family protein; [M] COG0845 Membrane-fusion protein.
 
   0.606
msbA
Lipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
 
 
  
0.542
CH54_875
ABC transporter family protein; [V] COG1132 ABC-type multidrug transport system, ATPase and permease components.
 
 
  
0.535
Your Current Organism:
Yersinia kristensenii
NCBI taxonomy Id: 28152
Other names: ATCC 33638, CCUG 11294, CCUG 8241, CIP 80.30, DSM 18543, JCM 7576, NCTC 11471, Y. kristensenii, strain 105
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