| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CH54_3173 | fabG9 | CH54_3173 | CH54_500 | Isochorismatase family protein; [Q] COG1535 Isochorismate hydrolase. | Short chain dehydrogenase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.554 |
| cobO | fabG9 | CH54_501 | CH54_500 | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Short chain dehydrogenase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.817 |
| cobO | sohB | CH54_501 | CH54_499 | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Serine dehydrogenase ase family protein; [OU] COG0616 Periplasmic serine proteases (ClpP class). | 0.494 |
| fabD | fabG9 | CH54_77 | CH54_500 | fabD: malonyl CoA-acyl carrier protein transacylase; [I] COG0331 (acyl-carrier-protein) S-malonyltransferase. | Short chain dehydrogenase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.526 |
| fabD | fadB | CH54_77 | CH54_2852 | fabD: malonyl CoA-acyl carrier protein transacylase; [I] COG0331 (acyl-carrier-protein) S-malonyltransferase. | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.673 |
| fabG9 | CH54_3173 | CH54_500 | CH54_3173 | Short chain dehydrogenase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Isochorismatase family protein; [Q] COG1535 Isochorismate hydrolase. | 0.554 |
| fabG9 | cobO | CH54_500 | CH54_501 | Short chain dehydrogenase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.817 |
| fabG9 | fabD | CH54_500 | CH54_77 | Short chain dehydrogenase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | fabD: malonyl CoA-acyl carrier protein transacylase; [I] COG0331 (acyl-carrier-protein) S-malonyltransferase. | 0.526 |
| fabG9 | fadB | CH54_500 | CH54_2852 | Short chain dehydrogenase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.635 |
| fabG9 | gutM | CH54_500 | CH54_1380 | Short chain dehydrogenase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | [K] COG4578 Glucitol operon activator. | 0.575 |
| fabG9 | nuoD | CH54_500 | CH54_3927 | Short chain dehydrogenase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | NADH dehydrogenase (quinone), D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. | 0.892 |
| fabG9 | pfkB | CH54_500 | CH54_4013 | Short chain dehydrogenase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | pfkB: 1-phosphofructokinase; [G] COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family. | 0.632 |
| fabG9 | sbcD | CH54_500 | CH54_3641 | Short chain dehydrogenase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Exonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.564 |
| fabG9 | sohB | CH54_500 | CH54_499 | Short chain dehydrogenase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Serine dehydrogenase ase family protein; [OU] COG0616 Periplasmic serine proteases (ClpP class). | 0.583 |
| fabG9 | srlA | CH54_500 | CH54_1376 | Short chain dehydrogenase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | EII-GUT: PTS system, glucitol/sorbitol-specific, IIC component family protein; [G] COG3730 Phosphotransferase system sorbitol-specific component IIC. | 0.569 |
| fadB | fabD | CH54_2852 | CH54_77 | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | fabD: malonyl CoA-acyl carrier protein transacylase; [I] COG0331 (acyl-carrier-protein) S-malonyltransferase. | 0.673 |
| fadB | fabG9 | CH54_2852 | CH54_500 | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | Short chain dehydrogenase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.635 |
| fadB | nuoD | CH54_2852 | CH54_3927 | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | NADH dehydrogenase (quinone), D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. | 0.544 |
| gutM | fabG9 | CH54_1380 | CH54_500 | [K] COG4578 Glucitol operon activator. | Short chain dehydrogenase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.575 |
| gutM | srlA | CH54_1380 | CH54_1376 | [K] COG4578 Glucitol operon activator. | EII-GUT: PTS system, glucitol/sorbitol-specific, IIC component family protein; [G] COG3730 Phosphotransferase system sorbitol-specific component IIC. | 0.978 |