Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
trpC[E] COG0134 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (458 aa)    
Predicted Functional Partners:
trpG
trpG_papA: glutamine amidotransferase of anthranilate synthase/aminodeoxychorismate synthase family protein; [EH] COG0512 Anthranilate/para-aminobenzoate synthases component II.
  
 0.999
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
 0.999
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
 0.999
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
 
 0.999
trpE
trpE_proteo: anthranilate synthase component I; [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I.
 
 0.997
pabA
trpG_papA: glutamine amidotransferase of anthranilate synthase/aminodeoxychorismate synthase family protein; [EH] COG0512 Anthranilate/para-aminobenzoate synthases component II.
  
 0.992
pabB
pabB: aminodeoxychorismate synthase, component I; [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I.
 
 0.990
CH54_882
Salicyl_syn: salicylate synthase; [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I.
 
 
 0.985
CH54_1059
Glycosyl transferase family, helical bundle domain protein; [E] COG0547 Anthranilate phosphoribosyltransferase.
 
  
 0.894
pheA
CM_P_1: chorismate mutase; [E] COG0077 Prephenate dehydratase.
 
  
 0.771
Your Current Organism:
Yersinia kristensenii
NCBI taxonomy Id: 28152
Other names: ATCC 33638, CCUG 11294, CCUG 8241, CIP 80.30, DSM 18543, JCM 7576, NCTC 11471, Y. kristensenii, strain 105
Server load: low (14%) [HD]