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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tonBHypothetical protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. (252 aa)    
Predicted Functional Partners:
exbD
exbD_1: TonB system transport protein ExbD; [U] COG0848 Biopolymer transport protein.
 
 
 0.984
foxA
tonB-siderophor: TonB-dependent siderophore receptor family protein; [P] COG1629 Outer membrane receptor proteins, mostly Fe transport.
  
 
 0.966
exbB
exbB: tonB-system energizer ExbB; [U] COG0811 Biopolymer transport proteins.
  
 
 0.957
tolR
Protein TolR; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
 
 
 0.935
fepA
tonB-siderophor: TonB-dependent siderophore receptor family protein; [P] COG4771 Outer membrane receptor for ferrienterochelin and colicins.
  
 
 0.884
tolQ
Protein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
  
 
 0.860
CH54_880
tonB dependent receptor family protein; [P] COG1629 Outer membrane receptor proteins, mostly Fe transport.
 
 
 0.859
hxuC_2
tonB-hemlactrns: TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; [P] COG1629 Outer membrane receptor proteins, mostly Fe transport.
 
 
 0.848
fhuF
fe_III_red_FhuF: siderophore-iron reductase FhuF; [R] COG4114 Uncharacterized Fe-S protein.
   
    0.847
hemR
tonB-hemlactrns: TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; [P] COG1629 Outer membrane receptor proteins, mostly Fe transport.
 
 
 0.818
Your Current Organism:
Yersinia kristensenii
NCBI taxonomy Id: 28152
Other names: ATCC 33638, CCUG 11294, CCUG 8241, CIP 80.30, DSM 18543, JCM 7576, NCTC 11471, Y. kristensenii, strain 105
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