STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cdgR[T] COG2200 FOG: EAL domain. (243 aa)    
Predicted Functional Partners:
CH54_585
GGDEF: diguanylate cyclase domain protein; [T] COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.
 
 
 0.797
flhD
Flagellar transcriptional activator family protein; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family.
    
 
 0.695
cph2_2
GGDEF: diguanylate cyclase domain protein; [T] COG2199 FOG: GGDEF domain.
 
 
 0.689
gmr_2
GGDEF: diguanylate cyclase domain protein; [T] COG2200 FOG: EAL domain.
 
 
 0.688
barA
HAMP domain protein; [T] COG0642 Signal transduction histidine kinase.
  
  
 0.672
gmr_1
GGDEF: diguanylate cyclase domain protein; [T] COG2202 FOG: PAS/PAC domain.
 
 
 0.646
fis
Bacterial regulatory, Fis family protein; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family.
    
 
 0.631
arcB
Sensory box protein; [T] COG0642 Signal transduction histidine kinase.
  
 
 0.630
gmr_3
GGDEF: diguanylate cyclase domain protein; [T] COG2200 FOG: EAL domain.
 
 
 0.628
ycgG_1
[T] COG2200 FOG: EAL domain.
  
     0.616
Your Current Organism:
Yersinia kristensenii
NCBI taxonomy Id: 28152
Other names: ATCC 33638, CCUG 11294, CCUG 8241, CIP 80.30, DSM 18543, JCM 7576, NCTC 11471, Y. kristensenii, strain 105
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