node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
gutQ | kdsA | CH54_1382 | CH54_651 | kpsF: sugar isomerase, KpsF/GutQ family protein; [M] COG0794 Predicted sugar phosphate isomerase involved in capsule formation. | KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase; [M] COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family. | 0.891 |
gutQ | kdsB | CH54_1382 | CH54_4104 | kpsF: sugar isomerase, KpsF/GutQ family protein; [M] COG0794 Predicted sugar phosphate isomerase involved in capsule formation. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.878 |
gutQ | kdsC | CH54_1382 | CH54_3015 | kpsF: sugar isomerase, KpsF/GutQ family protein; [M] COG0794 Predicted sugar phosphate isomerase involved in capsule formation. | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family protein; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | 0.890 |
gutQ | lpxA | CH54_1382 | CH54_3532 | kpsF: sugar isomerase, KpsF/GutQ family protein; [M] COG0794 Predicted sugar phosphate isomerase involved in capsule formation. | acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.817 |
gutQ | lpxB | CH54_1382 | CH54_3533 | kpsF: sugar isomerase, KpsF/GutQ family protein; [M] COG0794 Predicted sugar phosphate isomerase involved in capsule formation. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.798 |
gutQ | lpxC | CH54_1382 | CH54_1773 | kpsF: sugar isomerase, KpsF/GutQ family protein; [M] COG0794 Predicted sugar phosphate isomerase involved in capsule formation. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.851 |
gutQ | lpxD | CH54_1382 | CH54_3530 | kpsF: sugar isomerase, KpsF/GutQ family protein; [M] COG0794 Predicted sugar phosphate isomerase involved in capsule formation. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD; Catalyzes the N-acylation of UDP-3-O- (hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell; Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.819 |
gutQ | lpxK | CH54_1382 | CH54_4100 | kpsF: sugar isomerase, KpsF/GutQ family protein; [M] COG0794 Predicted sugar phosphate isomerase involved in capsule formation. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.867 |
gutQ | waaA | CH54_1382 | CH54_2651 | kpsF: sugar isomerase, KpsF/GutQ family protein; [M] COG0794 Predicted sugar phosphate isomerase involved in capsule formation. | Glycosyl transferases group 1 family protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.848 |
kdsA | gutQ | CH54_651 | CH54_1382 | KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase; [M] COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family. | kpsF: sugar isomerase, KpsF/GutQ family protein; [M] COG0794 Predicted sugar phosphate isomerase involved in capsule formation. | 0.891 |
kdsA | kdsB | CH54_651 | CH54_4104 | KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase; [M] COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.868 |
kdsA | kdsC | CH54_651 | CH54_3015 | KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase; [M] COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family. | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family protein; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | 0.990 |
kdsA | kdsD | CH54_651 | CH54_3016 | KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase; [M] COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family. | kpsF: sugar isomerase, KpsF/GutQ family protein; [M] COG0794 Predicted sugar phosphate isomerase involved in capsule formation. | 0.988 |
kdsA | lpxA | CH54_651 | CH54_3532 | KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase; [M] COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family. | acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.817 |
kdsA | lpxB | CH54_651 | CH54_3533 | KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase; [M] COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.846 |
kdsA | lpxC | CH54_651 | CH54_1773 | KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase; [M] COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.846 |
kdsA | lpxD | CH54_651 | CH54_3530 | KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase; [M] COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD; Catalyzes the N-acylation of UDP-3-O- (hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell; Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.850 |
kdsA | lpxK | CH54_651 | CH54_4100 | KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase; [M] COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.850 |
kdsA | waaA | CH54_651 | CH54_2651 | KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase; [M] COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family. | Glycosyl transferases group 1 family protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.841 |
kdsB | gutQ | CH54_4104 | CH54_1382 | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | kpsF: sugar isomerase, KpsF/GutQ family protein; [M] COG0794 Predicted sugar phosphate isomerase involved in capsule formation. | 0.878 |