Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ompD[M] COG3203 Outer membrane protein (porin). (360 aa)    
Predicted Functional Partners:
ompA1
ompA-like transmembrane domain protein; [M] COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
  
 
 0.868
lpoB
Hypothetical protein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b). Belongs to the LpoB family.
  
     0.773
holD
DNA polymerase III psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.
  
     0.772
zapB
Hypothetical protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.
  
     0.770
tolC
type_I_sec_TolC: type I secretion outer membrane, TolC family protein; [MU] COG1538 Outer membrane protein.
  
  
 0.768
yhcB
Conserved hypothetical protein; [S] COG3105 Uncharacterized protein conserved in bacteria.
  
     0.766
mlaA
vacJ like lipofamily protein; [M] COG2853 Surface lipoprotein.
   
 
 0.765
ftsN
Cell division protein FtsN; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.
  
    0.757
CH54_3630
Hypothetical protein.
  
     0.748
CH54_991
asmA family protein; [M] COG2982 Uncharacterized protein involved in outer membrane biogenesis.
  
     0.747
Your Current Organism:
Yersinia kristensenii
NCBI taxonomy Id: 28152
Other names: ATCC 33638, CCUG 11294, CCUG 8241, CIP 80.30, DSM 18543, JCM 7576, NCTC 11471, Y. kristensenii, strain 105
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