Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lolE_2ftsX-like permease family protein; [V] COG0577 ABC-type antimicrobial peptide transport system, permease component. (385 aa)    
Predicted Functional Partners:
macB_4
ABC transporter family protein; [V] COG1136 ABC-type antimicrobial peptide transport system, ATPase component.
 
 
 0.976
CH54_707
YHS domain protein; [S] COG4393 Predicted membrane protein.
 
  
 0.960
resA
Thioredoxin family protein; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins.
 
     0.904
tpd
Fe2+ transport family protein; [P] COG3470 Uncharacterized protein probably involved in high-affinity Fe2+ transport.
 
     0.877
efeU_2
Iron permease FTR1 family protein; [P] COG0672 High-affinity Fe2+/Pb2+ permease.
 
     0.853
macB_3
ftsX-like permease family protein; [V] COG0577 ABC-type antimicrobial peptide transport system, permease component.
 
    
0.831
CH54_702
[C] COG2863 Cytochrome c553.
       0.773
lolA
Outer membrane lipocarrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
 
 
 
 0.748
macB_2
ABC transporter family protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
 
 
 0.732
lolD
Liporeleasing system, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.
 
 
 0.696
Your Current Organism:
Yersinia kristensenii
NCBI taxonomy Id: 28152
Other names: ATCC 33638, CCUG 11294, CCUG 8241, CIP 80.30, DSM 18543, JCM 7576, NCTC 11471, Y. kristensenii, strain 105
Server load: low (16%) [HD]