close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cimH2-hydroxycarboxylate transporter family protein; [C] COG3493 Na+/citrate symporter. (452 aa)    
Predicted Functional Partners:
maeA_1
Malic enzyme, NAD binding domain protein; [C] COG0281 Malic enzyme.
 
  
 0.618
citX
citrate_citX: holo-ACP synthase CitX; [HI] COG3697 Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase).
 
   
 0.610
citD
Citrate lyase acyl carrier protein; Covalent carrier of the coenzyme of citrate lyase.
 
   
 0.593
citA
Sensory box protein; [T] COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism.
 
  
 0.587
citC
[citrate (pro-3S)-lyase] ligase; Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase.
 
   
 0.583
maeB
Malic enzyme, NAD binding domain protein; [C] COG0281 Malic enzyme.
 
  
 0.577
citF
citF: citrate lyase, alpha subunit; [C] COG3051 Citrate lyase, alpha subunit.
 
   
 0.565
citE
hpcH/HpaI aldolase/citrate lyase family protein; [G] COG2301 Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family.
 
   
 0.555
dcuS
PAS fold family protein; [T] COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism.
 
  
 0.533
citB
[KT] COG4565 Response regulator of citrate/malate metabolism.
 
    0.521
Your Current Organism:
Yersinia kristensenii
NCBI taxonomy Id: 28152
Other names: ATCC 33638, CCUG 11294, CCUG 8241, CIP 80.30, DSM 18543, JCM 7576, NCTC 11471, Y. kristensenii, strain 105
Server load: low (30%) [HD]