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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uvrYBacterial regulatory s, luxR family protein; [TK] COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. (218 aa)    
Predicted Functional Partners:
barA
HAMP domain protein; [T] COG0642 Signal transduction histidine kinase.
 
 0.997
arcB
Sensory box protein; [T] COG0642 Signal transduction histidine kinase.
 
 
 0.815
uvrC
Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
     
 0.798
CH54_46
Bacterial extracellular solute-binding s, 3 family protein; [ET] COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.
  
 
 0.764
uhpB
[T] COG3851 Signal transduction histidine kinase, glucose-6-phosphate specific.
 
   0.714
adrA_2
GGDEF: diguanylate cyclase domain protein; [T] COG2202 FOG: PAS/PAC domain.
 
 
 
 0.713
nreB
[T] COG3851 Signal transduction histidine kinase, glucose-6-phosphate specific.
 
 
   0.704
lpxD
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD; Catalyzes the N-acylation of UDP-3-O- (hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell; Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
      
 0.681
rcsC_1
Response regulator; [T] COG0642 Signal transduction histidine kinase.
 
 
 
 0.646
rcsC_3
rcsC Alpha-Beta-Loop family protein; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.
   
 
 0.623
Your Current Organism:
Yersinia kristensenii
NCBI taxonomy Id: 28152
Other names: ATCC 33638, CCUG 11294, CCUG 8241, CIP 80.30, DSM 18543, JCM 7576, NCTC 11471, Y. kristensenii, strain 105
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